Sara
The Toxic Avenger
Wanda
Julie
Slug
Bozo
Mayor Belgoody
Melvin
Officer O'Clancy
Walter Harris
Chief of Police
Cigar Face
Knuckles
Nipples
Leroy
Frank
Rico
Mrs. Haskell
Fred
Johnny
Melvin's Mom
Tom Wrightson
Dr. Snodburger
Toxic Avenger's Voice (voice)
Barbie
Bully
Bozo's Friend
Ice Cream Man
Mayor's Secretary
Health Club Girl (uncredited)