Sherlock Holmes
Dr. Watson
Ann Brandon
Jerrold Hunter
Billy
Professor Moriarty
Sir Ronald Ramsgate
Inspector Bristol
Henchman Bassick
Mrs. Jameson, Brandon Housekeeper
Lloyd Brandon
Mrs. Hudson
Justice of the Court
Henchman Mateo
Lady Conyngham
Dawes, Moriarty's servant
Inquisitive Stranger
Tony Conyngham
Barrows - Moriarty's Attorney (uncredited)
Foreman of the Jury (uncredited)
Gates - Trial Prosecutor (uncredited)
Clerk of the Court (uncredited)
Tompkins (uncredited)
Denis Green (uncredited)
Tower Sentry (uncredited)
Guard (uncredited)
Constable (uncredited)
Bobby (uncredited)
Bobby (uncredited)
Bobby (uncredited)
Marine Sergeant (uncredited)
Cabby (uncredited)
Second Fake Constable (uncredited)
Conyngham Butler (uncredited)
Cockney (uncredited)
Pub Customer (uncredited)
Scotland Yard Man (uncredited)