Sherlock Holmes
Dr. John H. Watson
Major Duncan-Bleek
Inspector Lestrade
Vivian Vedder
Prof. William Kilbane
Lady Margaret Carstairs
Sands - Moran's Accomplice
Conductor Taking Tickets
Roland Carstairs
Mrs. Shallcross (uncredited)
Alf Shallcross (uncredited)
Senior Conductor (uncredited)
Mock the Undertaker (uncredited)
Baggage Car Guard (uncredited)
"Inspector MacDonald" (uncredited)
Mock Jr. (uncredited)
Dining Car Steward (uncredited)
Elderly gentleman on train station (uncredited)