Enola Holmes
Sherlock Holmes
Mycroft Holmes
Eudoria Holmes
Lord Tewkesbury
Lestrade
Miss Harrison
The Dowager
Linthorn
Edith
Mrs. Lane
Sir Whimbrel
Lady Tewkesbury
Seamstress
Station Master
Miss Gregory
Miss Gregory II
Footman
Gardener
Tea Shop Assistant
Fleet Street Hawker
Constable
Young Enola
Toddler Enola
Agitator
Porter
Grace Whitting
Newspaper Boy (House of Lords)
Newspaper Boy (Fleet Street)
Newspaper Editor
Boarding School Teacher
Miss Fox
Young Sherlock Holmes (uncredited)
Police Inspector (uncredited)
Hawker (uncredited)
Conductor (uncredited)