Garfield (voice)
Jon Arbuckle/ Caveman #1 / Junior / Soldier / Computer (voice)
Odie / Jester / Scientist #1 / Cave Cat Narrator (voice)
Chloe / Sara (voice)
Luigi / Black Bart (voice)
George Frideric Handel / Larry (voice)
Little Sara (voice)
Garfield's Mother / Sara's Mother (voice)
Older Sara (voice)
Commander Mendelson (voice)
God (voice)
Additional Voices (voice)