Three cases from The First 48 that feature families enveloped in personal tragedies. In New Orleans, two cousins have a deadly fight, in Memphis, a young couple disappear and their uncle's home holds a clue, and in Dallas, a woman brutally turns on her sister-in-law.

Three different approaches to suspect interviews are featured from The First 48. First, detectives in Cleveland sit down with friends and the suspect in the murder of a young mother, then the boyfriend of a missing woman is questioned in Harris County with hopes of finding the woman alive, and detectives in Memphis change strategy in an effort to get their murder suspect to talk.

Three cases from The First 48 where things get out of control in a heated moment. In Birmingham, a man's body is found burned after an argument with a friend; in New Orleans, a man with cancer gets a ride home that ends in his murder; and in Tulsa, a man visiting his son is killed in a jealous rage.

A look back at three cases from The First 48 where forensics played a pivotal role in solving homicides. In Harris County, detectives rely on fingerprints to solve a father's carjacking and murder. In Charlotte, NC, a slain woman's family finds justice through DNA; and in Minneapolis, ballistics is the key to solving a man shot during a street fight.

When there are no witnesses, homicide detectives face an uphill climb to find the truth. First, detectives in Cincinnati come across a bizarre homicide at an apartment fire. Then, in Memphis, solving a preacher’s murder hinges on a single fingerprint. And a Tulsa woman found dead leaves police a clue that might solve her own murder.

Three cases from The First 48 that were driven by revenge and resentment. In Mobile, a man is executed in a parking lot months after an altercation; in Harris County, TX, pressing charges in an attempted robbery leads to a man’s brutal murder; and in Tulsa, a gang member goes on the hunt after being called a name.

Three stories from The First 48 where a plan proved deadly for unwitting victims. In Dallas, a man is lured to his death in an abandoned apartment; a homeless man in Miami is brutally beaten with a rock; and a Tulsa woman’s plan to help her sister goes horribly wrong.

Three stories from The First 48 where a plan proved deadly for unwitting victims. In Dallas, a man is lured to his death in an abandoned apartment; a homeless man in Miami is brutally beaten with a rock; and a Tulsa woman’s plan to help her sister goes horribly wrong.

A look back at three First 48 cases where the victims were in the wrong place at the wrong time. In Tulsa, what appears to be a case of road rage turns out to be something else entirely. Then, a man is stabbed to death in his car and Tulsa detectives have a hard time believing his friend’s story of what happened. And investigators in Harris County must get to the bottom of a car wash shooting that leaves a man dead.

In Memphis, a woman is dragged to her death in broad daylight; in Harris County, a young mother is found with her throat slashed; in Miami, an ongoing battle between two gangs feels impossible to curtail as the body count rises.

Rookie detectives lead their first investigations in three cases from "The First 48" archive; in Louisville, Ky., a rookie leans on video surveillance to find a convenience store killer.

Homicide detectives attempt to understand puzzling motives for murder after a woman is attacked as payback for someone else, a barber is shot by someone who appears to be a friend and a man is targeted for defending a friend.

Veteran homicide detectives search for answers after a woman is killed in her Dallas home, a reluctant witness weighs whether to name the shooter in a homicide case in Memphis and a man gets shot in his own doorway in Dallas.

Examines three cases where homicides were committed in the name of love. First, in Dallas, a couple is shot to death on their doorstep, and detectives have to track down the killer as he goes on a multi-state crime spree. Then, in Louisville, a hearing-impaired man is stabbed in his doorway. And finally in Tulsa, a woman's body is found in a trash can. Can her death be linked to the murder of her fiance the year before?