Earp spots old buffalo hunter Jake Caster in a saloon. Jake lives with the his wife's tribe, the Cheyenne. He tells Earp his wife is dead as he eyes some soldiers. When one of the soldiers is killed, trouble erupts and Earp suspects Jake.

Wyatt Earp's propensity for playing the lone hand gets him trapped by his hated enemies, the Big T outfit, at Adobe Springs. His enemies, who greatly outnumber him, seek to starve him out. But word that Wyatt is in a real jam is spread by a cowhand grateful for past favors, and soon wuch old friends and strange characters - each grateful in his own way - quietly assemble to rescue Wyatt in an all-time famous gun battle with the Big T. These characters include Bat Masterson, Ben Thompson, Doc Holliday, John Wesley Hardin, Mannen Clements and others.