George Clooney receives the 46th AFI Life Achievement Award in a gala tribute at the Dolby Theatre in Los Angeles, California. Presenters and performers include Jennifer Aniston, Cate Blanchett, Don Cheadle, Amal Clooney, Nick Clooney, Courteney Cox, Miley Cyrus, Laura Dern, Julianna Margulies, Bill Murray and Shirley MacLaine.