The first episode, "The Real Man", looked at the historical evidence for the existence of Jesus, and documented his life from his birth to his temptation.

Episode two, "The Mission", discussed how Jesus became popular among Jews and Greeks, and why the Pharisees of the area might have seen him as a threat.

"The Final Hours", the third and final episode of Son of God, looked at Jesus's crucifixion, and presented some ideas as to how the traditional views of the crucifixion may conflict with how it really occurred. The episode concluded with the construction of a computer-generated animation of how Jesus may have appeared.