Three stories of living life to the fullest, despite illness, age or any obstacle.

Three inspiring people switch gears in life in order to pursue their dreams.

Jackie and David Siegel talk about building the largest home in America when the economy crashed in 2008.

Sisters Josie Cavaluzzi, Teresa Dalquist and Mary Bartnicki, all in their 80s, give their take on sex.

Documentarian Morgan Spurlock joins Jeff to talk about what makes a man.

A woman not feeling well checks herself into a hospital and comes out with her limbs amputated; an American is held hostage in Iraq for more than 300 days.

Reality stars Jeff Lewis and Zoila Chavez; a father changes his life to bring joy to his teen daughter; a man teaches his goofy dance all over the world.

A man who posted his phone number around New York City in order to find someone to talk to ends up changing people's lives; a couple rekindles their childhood love 40 years later.

Mike Rowe shares some of the unique jobs he has done on his hit TV show; an adult-toy reviewer; a fortune-cookie writer; the producer who comes up with the challenges on ``Survivor.''

A woman sets out to make a new friend every day for a year; a man conducts bizarre and fascinating life experiments; a blogger packs up and moves to another country every four months.