In the Season 2 premiere, Dr. Mehmet Oz discusses a man's chest pains; a man tells his wife about a tumor on his spine; a urology resident meets with patients; and ER nurses treat a woman's bizarre injury at New York-Presbyterian Hospital. Meanwhile, a trauma surgeon examines a man with multiple gunshot wounds at University Hospital in Newark, N.J.

An ER doctor treats a couple who were the victims of a violent home invasion; a former Wall Street banker reflects on changing her career to medicine; a Marine recalls his service and describes his deteriorating physical condition.

A doctor treats a student pilot whose instructor was killed in a plane crash; a urology resident discusses a surgical procedure with a patient; a cardiac surgeon thinks he can help a woman with a tumor on her heart. Also: Dr. Mehmet Oz investigates a police officer's mysterious stroke that he suffered on vacation with his family.

A nurse becomes a patient after inexplicably losing consciousness; a man who's about to be married gets alarming news from a cardiac surgeon; a trauma surgeon treats a man who was beaten with a hammer; a neurosurgeon tells a homeless man he needs surgery to repair damaged vertebrae in his neck

A man with a blood clot in his lungs is treated by an ER doctor, who later helps security guards subdue a violent patient. Elsewhere, a woman in need of a kidney transplant gets surprising news; a cardiac surgeon makes a promise to woman about to undergo heart surgery; and an ER doctor discusses a personal struggle.

A 2-year-old needs surgery to alter the flow of blood to her brain; an ER resident confronts police officers who are bothering one of her patients; a trauma surgeon discusses the high number of young males who are brought in with bullet wounds; a charismatic surgical resident impresses his patients and his superiors.