Peter and Mary Jane's big day arrives, but things aren't going to go to plan if Harry Osborn gets his way. With guests including Flash Thompson, Liz, Aunt May, Anna Watson, Felicia Hardy, J. Jonah Jameson, Robbie Robertson and Wilson Fisk, along with gate crashers including the Green Goblin, the Kingpin, Alistair Smythe, the Scorpion, the Black Cat, Herbert Landon, the Mega-Slayer, Norman Osborn, and an army of robot Goblin Warriors, it'll certainly be a day to remember.

After a visit from an "old friend" of the family, Peter travels to Russia to investigate the mystery of his parents disappearance, and runs into some old friends.

Still in Russia, Peter discovers that searching for clues to his family's past isn't easy when he has to battle the Insidious Six and the Red Skull.

Robbie and Peter encounter an old professor who knows about the Six Forgotten Warriors.

Spider-Man and the Warriors join forces to stop the Kingpin from activating the doomsday device.

Red Skull reveals his Doomsday Weapon, the powerful Electro.

Mary Jane and Peter arrive in Niagara Falls for their postponed honeymoon, but it is soon interrupted when Hydro-Man returns and kidnaps Mary Jane.

Peter is shocked by Mary Jane's new powers, so they seek Curt Connors' help in figuring everything out. Mary Jane tells them about a dream she's been having, which may be a clue to her disappearance. But Hydro-Man finds them and kidnaps her again.

Spider-Man is transported to an alien world, where he meets the Beyonder, a being who wants to see if good is stronger than evil. He then summons a group of the greatest villains from Earth to this world, telling Spider-Man to put together a group of heroes to fight them and save the planet.

Spider-Man summons the Black Cat from Earth, who despite her anger at being kidnapped, decides to help him fight the villains on the alien planet. The heroes must defeat the Red Skull, Doctor Octopus, and Alistair Smythe's robots while protecting a group of rebels, who are trying to take their planet back.

Dr. Doom reverts the Thing to his human form and holds the other heroes prisoner. In an attempt to free his friends, the Thing tells Dr. Doom about the Beyonder. Dr. Doom then steals the Beyonder's powers, but they begin manifesting themselves in the form of creatures from Dr. Doom's dreams.

Spider-Man finds himself in yet another dimension, where he meets himself.

Spider-Man is sent through several dimensions trying to fix time and seal away Spider-Carnage. Peter meets his would-be girlfriend Gwen Stacy and Stan Lee.