In the first of a new series, doctor Sue Mason and Sister Benita Wainwright prepare resus for Rory, a 56-year-old patient who has been found unconscious at home. Elsewhere, doctor George Kay treats 85-year-old Pearl, who is struggling for breath and has a racing heart, and 10-year-old Koby arrives in the hospital after chopping off the tip of his finger.

One of the department's new junior doctors treats a man with a suspected case of sepsis, that has been triggered by the tracheostomy tube he relies on to breathe. An 84-year-old woman is brought in by ambulance after falling down a flight of stairs and undergoes multiple x-rays to check for broken bones, while a 12-month-old baby needs treatment after having a fit.

There are complications when a woman who suffers from kidney failure is admitted with a heart condition, and two builders are rushed into casualty after a roof collapsed under them. Meanwhile, a 65-year-old Alan goes for a CT scan after an epileptic fit left him with a serious head wound, and doctors treat a 12-year-old boy who has been attacked by a dog.

When the red phone rings in the A&E department of Barnsley Hospital, staff rush to help a woman who has arrived in an ambulance and is struggling to breath. Former showbiz pianist Terry (84) comes in with a badly broken ankle and the fear he may never dance again.

Paramedics rush in Dean, a 30-year-old who has been admitted after being in a serious motorbike collision and may have spinal injuries. Elsewhere, doctors treat a 20-year-old with severe abdominal pain, and a 90-year-old with an injured finger.

The hospital struggles with a huge backlog of untreated patients from the night shift, as staff have a hard time ensuring that everyone id discharged or admitted within 4 hours of arrival. An 85-year-old motorist is treated for a severe head injury after skidding on ice, her car ending up on its roof. A woman who tripped while shopping fears that a broken ankle will jeopardise her plans to go on a cruise.

A toddler is rushed in with suspected sepsis, a life-threatening condition that attacks the organs, and a large team of specialists administer high-strength antibiotics. Elsewhere, advanced nurse practitioner Cheryl is looking after 57-year-old Michael, who has come in with severe abdominal pain, and an 87-year-old woman is rushed in after being knocked over by a car.

Doctors treat Craig, a window-fitter who has fallen from a ladder and has been knocked unconscious. He has a huge gash to the back of his head but the medical staff are concerned he may have also seriously injured his neck and spine. Meanwhile, advanced nurse practitioner Dave Sagol meets 61-year-old June who has been rushed into the hospital with swollen legs and having difficulty breathing.