While covering the news at the Mardi Gras, Audrey and Animal interview Paul Dimanche, a wealthy business mogul who represents one of the oldest and richest families from the French Quarter in the Big Easy. However, Audrey discovers that several of Paul's businesses in the city are being attacked by a mysterious mutants and she summons H.E.A.T. to deal with the problem.

Off the New Jersey coast, H.E.A.T. encounters the Deep-Dweller, a giant frogfish that has wandered into shallow waters.